Many of the complicated folded shapes that type mammalian tissues might be defined with quite simple directions, bioengineers report. By patterning mechanically lively mouse or human cells to skinny layers of extracellular fibers, the researchers might create bowls, coils, and ripples out of residing tissue. The cells collaborated mechanically by means of an online of those fibers to fold themselves up in predictable methods, mimicking pure developmental levels.

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